Rickettsial hemolysis: adsorption of rickettsiae to erythrocytes.
نویسندگان
چکیده
The hemolysis of sheep red blood cells by Rickettsia prowazeki has been characterized. A requirement for the adsorption of the rickettsia to the erythrocyte was indicated. No indication of the production of a soluble hemolysin was observed. Neither adsorption nor hemolysis can proceed at 0 C. The hemolytic process is rapid with a half-time of less than 30 min, and both the rate and extent are proportional to the number of rickettsiae present.
منابع مشابه
Rickettsial hemolysis: rapid method for enumeration of metabolically active typhus rickettsiae.
A new assay is described for enumerating biologically active typhus rickettsiae (Madrid E strain), based on adsorption of rickettsiae to erythrocytes in the presence of NaF (which allows adsorption but not lysis) and lysis in the presence of anti-Rickettsia prowazeki immune serum (which allows only a single round of lysis). The number of lysed erythrocytes is then used to estimate the number of...
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ورودعنوان ژورنال:
- Infection and immunity
دوره 7 1 شماره
صفحات -
تاریخ انتشار 1973